RT @ASLresearch: Anyone who wants to talk about the latest findings in gene-editing to prevent deafness (Yeh et al., 2020) must do so in li…
Anyone who wants to talk about the latest findings in gene-editing to prevent deafness (Yeh et al., 2020) must do so in light of C. Padden & J. Humphries (2020): "Who Goes First?" Yeh: https://t.co/1q4MUSm1nW Padden & Humphries: https://t.co/Dq5SW
RT @JulesGrunewald: In vivo #base_editing by Yeh & Shubina-Oleinik @liugroup & Holt Lab out in @ScienceTM: AID-based CBE (split AAV) inject…
#Audition 👂#surdité 🔇: la réparation d'une seule mutation du gène #Tmc1 dans les cellules sensorielles de l'oreille interne de #souris 🐭a suffit pour restaurer transitoirement l'audition des basses fréquences 4 semaines après l'injection 👍🧐https://t.co/pP9
The treatment reversed the mutation of the TMC1, improved sensory transduction, and partially restored hearing in mice. "In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness."
RT @JulesGrunewald: In vivo #base_editing by Yeh & Shubina-Oleinik @liugroup & Holt Lab out in @ScienceTM: AID-based CBE (split AAV) inject…
"In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness" Yeh WH, Shubina-Oleinik O [..] Holt JR, Liu DR. Sci Transl Med 2020-06-03. https://t.co/RdJBhzMEzA "split to deliver AID
遺伝治療は、既に白血病や網膜の病気に対して使われる段階まできている。 今後、筋ジストロフィーや神経病に使われるようになることは明らか!
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness https://t.co/tAtwwOIDAM
RT @JulesGrunewald: In vivo #base_editing by Yeh & Shubina-Oleinik @liugroup & Holt Lab out in @ScienceTM: AID-based CBE (split AAV) inject…
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness https://t.co/5sGdnj7vMN
RT @JulesGrunewald: In vivo #base_editing by Yeh & Shubina-Oleinik @liugroup & Holt Lab out in @ScienceTM: AID-based CBE (split AAV) inject…
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness https://t.co/sAfneUA5Yx
In vivo #base_editing by Yeh & Shubina-Oleinik @liugroup & Holt Lab out in @ScienceTM: AID-based CBE (split AAV) injected into mouse inner ear to revert recessive #deafness-causing point mutation. 50% WT allele restored & partial rescue of hear