李岳倫癌症/科學素養研究室,
《溫故知新》 正思考如何利用腫瘤微環境的研究於抗癌藥物治療與抗藥性,利用大數據策略,評估既有藥物處理後所有可能出現的變化,然後找出塑造最佳腫瘤微環境的標的藥物。 -----------------------------------------------…
《溫故知新》 正思考如何利用腫瘤微環境的研究於抗癌藥物治療與抗藥性,利用大數據策略,評估既有藥物處理後所有可能出現的變化,然後找出塑造最佳腫瘤微環境的標的藥物。 -----------------------------------------------…
FMD- a lot of cancer drugs don't work the way they're supposed to! https://stm.sciencemag.org/content/11/509/eaaw8412/tab-articl…
PHAR 508... worth reading.
為什麼 97% 抗癌藥物研發都失敗了? 上個月到美國參加了 2019 癌症生物學: 微環境與轉移會議,以更新一下目前在微環境、癌細胞異質性 (Heterogeneity)、藥物抗性機制、塑性與缺氧 (Plasticity and Hypoxia)、轉移與休…
Drugs may not do what we think they do, according to a new study in Science Magazine. Researchers at Cold Spring Harbor…
The majority of proposed anticancer treatments do not succeed in advancing to clinical use because of problems with efficacy or…
La toxicidad fuera de rango es un mecanismo de acción común de medicamentos contra el cáncer
Cancer drugs don't always work as intended, researchers warn. http://bit.ly/2lKF1G2
The science is a bit dense on this one, but the gist: these drugs don't do what we think they do. #cancer #Crispr #toxicity
흥미있는 논문이 나와서 잠깐 소개합니다. 아래 트윗은 논문의 책임저자의 요약입니다. https://twitter.com/jsheltzer/status/1171850294910750721?s=21 현대의 의약품 개발과정에서 실패율…
Off target toxicity is a huge problem in cancer clinical trials... https://www.nytimes.com/2019/09/11/health/cancer-drugs-protei…