2/7 I agree that amyloid itself does not drive the clinical phenotype, yet, amyloid clearly drives tau accumulation, which in turn drives neurodegeneration and the development of symptoms. https://t.co/tJVnFJvvlD https://t.co/b3vSNGblNw
Amyloid and tau are widely thought to be key players in AD, with tau having a relatively closer relation (in time and space) to neurodegeneration and resulting cognitive dysfunction patterns https://t.co/WVsfcQA7fk
RT @BayerFoundation: While Alzheimer's disease is assumed to be initiated by the accumulation of amyloid plaques, the downstream developmen…
RT @BayerFoundation: While Alzheimer's disease is assumed to be initiated by the accumulation of amyloid plaques, the downstream developmen…
While Alzheimer's disease is assumed to be initiated by the accumulation of amyloid plaques, the downstream development of neurofibrillary tau tangles is the major culprit that drives neurodegeneration as shown by this great tau-PET study by @relajoie htt
Interesting article about the prognostic value of tau PET compared to amyloid PET for the prediction of AD-induced brain atrophy: "Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET" ht
#38 Tau PET, but not amyloid PET, predicts atrophy on follow-up as seen with structural MRI #PaperPerDayChallenge https://t.co/cgStprRLwz
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET. Supports tau pathology as a major driver of local neurodegeneration and tau-PET as a precision medicine tool. https://t.co/Q9RqbwWF71
RT @lockhartbrains: Register for @ISTAART Journal Club Meet the Author program on Th 2/4 12p eastern. Renaud La Joie: https://t.co/8136StdO…
Register for @ISTAART Journal Club Meet the Author program on Th 2/4 12p eastern. Renaud La Joie: https://t.co/8136StdOUy Leonardo Iaccarino: https://t.co/qWv541JbQk More info/Register here! https://t.co/G3twxc9jrX
RT @syinvesting: @biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected wi…
RT @syinvesting: @biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected wi…
RT @syinvesting: @biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected wi…
RT @ScienceTM: A longitudinal imaging study of patients with early #Alzheimers disease reveals that the buildup of harmful tau proteins in…
Is the Tau protein the Achilles’ Heel for Alzheimer's disease? The protein, once seen as a secondary player, has taken a leading role in combating neurodegenerative illnesses. #Science #neuroscience @sciam 👇 https://t.co/1rsrdC0jvD https://t.co/0xFNisSE10
RT @syinvesting: @biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected wi…
RT @syinvesting: @biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected wi…
@biospace @NatureMedicine @ScienceMagazine A study published in @ScienceTM in Jan '20 found that baseline tau (detected with FTP-PET), but not beta-amyloid, predicted the degree and spatial distribution of cortical atrophy in #Alzheimers disease over the s
RT @LiGanLab: #Tau2020-1: a overview of Tau-PET for non-AD tauopathies by Dr. Gil Rabinovici #Tau2020 @alzassociation @RCFNeuro @CurePSP…
RT @LiGanLab: #Tau2020-1: a overview of Tau-PET for non-AD tauopathies by Dr. Gil Rabinovici #Tau2020 @alzassociation @RCFNeuro @CurePSP…
#Tau2020-1: a overview of Tau-PET for non-AD tauopathies by Dr. Gil Rabinovici #Tau2020 @alzassociation @RCFNeuro @CurePSP and their recent study of a longitudinal analysis with AD, showing tau-PET signal could predict brain atrophy at later stages http
RT @ScienceTM: A longitudinal imaging study of patients with early #Alzheimers disease reveals that the buildup of harmful tau proteins in…
RT @ciberned: #Investigación🔬: Científicos de la @universityofcalifornia apuntan a que la proteína #TAU de #Alzheimer es más eficaz para pr…
RT @ciberned: #Investigación🔬: Científicos de la @universityofcalifornia apuntan a que la proteína #TAU de #Alzheimer es más eficaz para pr…
@lejlaHUNHM @biogen EMERGE was sig on the CDR scale at the higher dose- with sample augment post futility analysis. Sketchy. Tau and b-amyloid both indicators in AD, though tau not targeted by Aduc. Leery of push to launch with https://t.co/YYMEzv9zSX and
RT @ciberned: #Investigación🔬: Científicos de la @universityofcalifornia apuntan a que la proteína #TAU de #Alzheimer es más eficaz para pr…
#Investigación🔬: Científicos de la @universityofcalifornia apuntan a que la proteína #TAU de #Alzheimer es más eficaz para predecir la aparición de la enfermedad que la proteína #BetaAmiloidemiloide. ➡ El estudio ha sido publicado en @ScienceMagazine. ht
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
@Nina_BSil @Alzheimers_NIH @UCSFmac @relajoie @JoeBalintfy "...tau pathology is a major driver of local neurodegeneration and highlight the relevance of tau-PET as a precision medicine tool..." https://t.co/KTiboFfexl #metabolomics can be used to gain
RT @Dr_Alex_Crimi: #Alzheimer : Tangle Density Foretells How Fast a Person’s Brain Will Shrink https://t.co/HWLhNWqmOv original paper: http…
Prospective longitudinal #atrophy in #AlzheimersDisease correlates with the #intensity and #topography of baseline tau-PET https://t.co/pQYsFqVWM9 | via @ScienceTM @UCSF
RT @UCSFmac: Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET. Test…
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET. Tested whether β-amyloid and tau-PET could predict brain atrophy. https://t.co/cjD33YkTAo @relajoie @jesseaaronbrown @leoiacca @Zachar
RT @SimonDuchesne: Big thanks to the UCSF group for using our MRI Freesurfer normative code and data, in "Prospective longitudinal atrophy…
RT @SimonDuchesne: Big thanks to the UCSF group for using our MRI Freesurfer normative code and data, in "Prospective longitudinal atrophy…
RT @SimonDuchesne: Big thanks to the UCSF group for using our MRI Freesurfer normative code and data, in "Prospective longitudinal atrophy…
Big thanks to the UCSF group for using our MRI Freesurfer normative code and data, in "Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET" by @relaJoie et al: https://t.co/PTlulivyH2
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
#Alzheimer : Tangle Density Foretells How Fast a Person’s Brain Will Shrink https://t.co/HWLhNWqmOv original paper: https://t.co/qr6B70gC8l #neuroimaging #brain #neurodegeneration . @Alzh_Fondation .@MolNeuro .@Neurodeg https://t.co/dhxitohUqY
RT @ApostolovaLiana: Thanks, @relajoie and @UCSFmac, for a wonderful journey examining the progression of neurodegeneration and proving som…
RT @ApostolovaLiana: Thanks, @relajoie and @UCSFmac, for a wonderful journey examining the progression of neurodegeneration and proving som…
RT @relajoie: Our @ScienceTM paper (https://t.co/rp6GaK62qM) is also the first one for which I uploaded all the voxelwise maps onto Neurova…
Sharing raw data is great, but I think it is equally important to share statistical maps. Thanks Renaud!!
A new study suggests that #PET imaging of #tau “tangles”, but not #amyloid plaques, can predict the location of future brain atrophy in Alzheimer's patients. https://t.co/zxqopIwryu @UCSFmac @relajoie #alzheimers https://t.co/rW51cU6tjJ
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @silex_transl: #AD 患者の脳萎縮の最初のPETサインはAβでなく#タウに出る。初期症状患者32人の長期追跡で示す。局所脳変性のメジャードライバーはタウ病変である、と:UCSF。 https://t.co/zVQil2NXOJ
#AD 患者の脳萎縮の最初のPETサインはAβでなく#タウに出る。初期症状患者32人の長期追跡で示す。局所脳変性のメジャードライバーはタウ病変である、と:UCSF。 https://t.co/zVQil2NXOJ
@HealthspanNow Nice article. Bu let's call it the 'precision diagnostics' era. https://t.co/eyYuSohlAV @brianedwardsmd
RT @ScienceTM: A longitudinal imaging study of patients with early #Alzheimers disease reveals that the buildup of harmful tau proteins in…
A longitudinal imaging study of patients with early #Alzheimers disease reveals that the buildup of harmful tau proteins in the brain predicts the location and severity of atrophy in brain tissues later on. @UCSF #TauPet #PETimaging https://t.co/kV2YEBEWe9
Prospective longitudinal atrophy in #alzheimers disease correlates with the intensity and topography of baseline tau-PET. https://t.co/bM69ny7q43
RT @PSPAssociation: “This is an important study confirming the prognostic importance of Tau for disease progression and the value of Tau PE…
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET | Science Translational Medicine https://t.co/vPv9zVbjPF
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @serotonin_nin: タウPETで将来のアルツハイマーの脳萎縮の予測が可能になるってよ。これ凄いよ。 たしか従来まではタウを生きている脳で測定することは不可能とされていたんだけど、フロータウシピルと呼ばれる分子を注射することによって可能になるってよ。 htt…
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @CambridgeFTD: Further evidence for the importance of Tau burden in predicting progression of Alzheimer's ... https://t.co/0bsCRlkvHH an…
RT @PSPAssociation: “This is an important study confirming the prognostic importance of Tau for disease progression and the value of Tau PE…
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
@relajoie :-) wow
Trending on PubMed: Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. https://t.co/tQd1g3C9qC
タウPETで将来のアルツハイマーの脳萎縮の予測が可能になるってよ。これ凄いよ。 たしか従来まではタウを生きている脳で測定することは不可能とされていたんだけど、フロータウシピルと呼ばれる分子を注射することによって可能になるってよ。 https://t.co/nH0YSyaJl4
RT @PSPAssociation: “This is an important study confirming the prognostic importance of Tau for disease progression and the value of Tau PE…
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
“This is an important study confirming the prognostic importance of Tau for disease progression and the value of Tau PET scanning. We must remember PSP-Tau ‘junk protein’ is different to Alzheimer-Tau and additional research on Tau in PSP & CBD is ess
Further evidence for the importance of Tau burden in predicting progression of Alzheimer's ... https://t.co/0bsCRlkvHH and the need to invest in large longitudinal studies Does the same apply to FTLD-tau-opathies?? Watch this space... @wellcometrust @Camb
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
RT @NatRevNeurol: Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
Tau pathology predicts future brain atrophy in individuals with early Alzheimer disease https://t.co/ZHZ1aZvyWP
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET https://t.co/s2dN5ZTlCs
RT @cesopenko: Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET | S…
RT @Biotech2050: Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET h…
RT @mocost: Tau "far surpasses amyloid in predicting toll on brain tissue" https://t.co/YxGorEwRti "Quantitative analyses showed that the g…
RT @mocost: Tau "far surpasses amyloid in predicting toll on brain tissue" https://t.co/YxGorEwRti "Quantitative analyses showed that the g…
RT @mocost: Tau "far surpasses amyloid in predicting toll on brain tissue" https://t.co/YxGorEwRti "Quantitative analyses showed that the g…
RT @mocost: Tau "far surpasses amyloid in predicting toll on brain tissue" https://t.co/YxGorEwRti "Quantitative analyses showed that the g…
Tau "far surpasses amyloid in predicting toll on brain tissue" https://t.co/YxGorEwRti "Quantitative analyses showed that the global intensity of tau-PET, but not β-amyloid–PET, signal predicted the rate of subsequent atrophy" https://t.co/B64zQ2ZGTt https
Research article on Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET https://t.co/Hkt2Pe1DeU
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET https://t.co/rNoF3iEtOQ
RT @cesopenko: Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET | S…
RT @bess_frost: Lovely longitudinal tau and amyloid beta PET study from Gil Rabinovici and colleagues - positive tau PET can predict subseq…
RT @bess_frost: Lovely longitudinal tau and amyloid beta PET study from Gil Rabinovici and colleagues - positive tau PET can predict subseq…